Enzalutamide for prostate cancer is four 40 mg tablets a day. Here is what 30 days cost in seven places, from official price lists.
Researched with AI assistance; every figure is checked against the primary source cited on this page before publishing. How we work →
Xtandi (enzalutamide) is taken as 160 mg once a day — four 40 mg capsules or tablets, or two 80 mg tablets (FDA label) — so 30 days = 120 × 40 mg. Pfizer charges the same for 120 × 40 mg and 60 × 80 mg. European packs hold 112 tablets of 40 mg; we scale to 120 (our calculation: pack price ÷ 112 × 120). US dollars at European Central Bank reference rates of November 6, 2026. The price types differ — list price, negotiated price, retail price — and are labelled.
XTANDI / ENZALUTAMIDE · 30 DAYS = 120 × 40 MG
Price by country, November 2026
Packs of 112 scaled to 120 tablets (our calculation). No official price in Germany.
| Country | Official price | 30 days in US dollars | What a patient typically pays |
|---|---|---|---|
| 🇺🇸 United States (list) | $15,352.94 for 120 × 40 mg or 60 × 80 mg (Pfizer, as of Mar 10, 2026) | $15,353 | — |
| 🇺🇸 United States (Medicare, 2027) | $7,004 negotiated price per 30-day supply, from Jan 1, 2027 (CMS); $61.924219 per 40 mg capsule | $7,431 | Depends on the Part D plan and coverage phase |
| 🇬🇧 United Kingdom | Enzalutamide 40 mg (Astellas) £2,734.67 for 112 tablets (NHS price) | $3,922 | £9.90 per item in England; free in Scotland, Wales and Northern Ireland |
| 🇨🇭 Switzerland | Xtandi CHF 3,137.65 for 112 tablets (public price; limitation) | $4,105 | 10% share after the annual deductible |
| 🇫🇷 France | Xtandi €2,821.58 for 112 tablets (official price excluding dispensing fee) | $3,375 | Fully reimbursed (100%) |
| 🇦🇹 Austria | Xtandi €2,623.25 for 112 tablets (social-insurance price excl. VAT; effective price may be lower under a price model) | $3,138 | €7.55 prescription fee per pack; insurer approval needed first |
| 🇳🇱 Netherlands | Xtandi €3,146.79 for 112 tablets, €28.10 per tablet (average pharmacy price) | $3,764 | Fully reimbursed; counts toward the annual deductible |
| 🇩🇪 Germany | No statutory price ceiling (Festbetrag) for enzalutamide; no official price found | — | — |
We compare prices; we do not recommend where to buy medicine. Cancer treatment decisions belong with your oncology team.
The $7,004 is the price Medicare negotiated under the Inflation Reduction Act for a 30-day supply, effective January 1, 2027. CMS’s data file sets $61.924219 per 40 mg capsule, or $7,431 for 120 (our calculation). In 2024 about 35,000 people with Medicare Part D used Xtandi, and Part D spent $3.40 billion on it before rebates (CMS).
Austria, France, the Netherlands, the UK and Switzerland publish an official price for enzalutamide 40 mg — about $3,138 to $4,105 for 120 tablets at ECB rates, or 20% to 27% of the US list price (our calculation: $3,138 ÷ $15,353 and $4,105 ÷ $15,353). Medicare’s 2027 price is still about 1.8 times the Swiss price (our calculation: $7,431 ÷ $4,105).
Since 2026 the NHS lists Astellas’s product as “Enzalutamide 40mg tablets” at £2,734.67 for 112; the Xtandi pack is marked discontinued from May 29, 2026 (dm+d). In Germany the Joint Federal Committee found a hint of minor added benefit for non-metastatic, castration-resistant high-risk prostate cancer (November 5, 2020) and no proven added benefit with hormone therapy in metastatic hormone-sensitive prostate cancer (November 19, 2021).
Pfizer lists 120 Xtandi 40 mg capsules or tablets at $15,352.94 (March 10, 2026). Medicare’s negotiated price from January 1, 2027 is $7,004 for a 30-day supply (CMS). In Europe, 112 tablets of 40 mg cost €2,623.25 in Austria (excl. VAT), €2,821.58 in France, €3,146.79 in the Netherlands, £2,734.67 in the UK and CHF 3,137.65 in Switzerland — about $3,138 to $4,105 for 120 tablets at ECB rates.
No: Pfizer lists 60 × 80 mg tablets at the same $15,352.94 as 120 × 40 mg (March 10, 2026).
Pfizer’s price disclosure lists no generic (“N/A”), CMS negotiates only drugs without generic competition, and the Dutch price list shows only Xtandi and parallel imports.
In England each prescription item costs £9.90; in France it is fully reimbursed; in Switzerland insured patients pay a 10% share after the deductible; in Austria a €7.55 prescription fee after the insurer approves it; in the Netherlands it is fully reimbursed but counts toward the annual deductible. In Medicare, it depends on the Part D plan.
The NHS dictionary (dm+d) lists Astellas’s 40 mg tablets under the generic name at £2,734.67 for 112 since March 27, 2026, and marks the Xtandi-branded pack discontinued from May 29, 2026.
Wellness Vision does not sell medicine, recommend pharmacies or suppliers, or take payments from drug makers. Every price above comes from the official source cited; currency conversions and 30-day figures are our own calculations, shown with their formula. This is a cost comparison, not medical advice.
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