The same biologic, etanercept 50 mg once a week — four pens priced from official databases in seven places, with biosimilars where they are listed.
Researched with AI assistance; every figure is checked against the primary source cited on this page before publishing. How we work →
Enbrel 50 mg, the usual adult dose of one injection a week, so four pens or syringes ≈ 28 days. Each country's own official price for a pack of four; where a country lists only packs of two, we double it (our calculation). US prices are per pen and multiplied by four (our calculation). US dollars at European Central Bank reference rates of October 30, 2026.
ENBREL (ETANERCEPT) 50 MG · 4 WEEKLY PENS = 28 DAYS
Price by country, November 2026
US figures are per-pen prices × 4 (our calculation). Switzerland lists Enbrel only in packs of 2 (× 2). Biosimilars are cheaper in several countries — see the table.
| Country | Official price | 30 days in US dollars | What a patient typically pays |
|---|---|---|---|
| 🇺🇸 United States (list) | $2,141.37 per pen or syringe (Amgen, as of Sept 8, 2026) | $8,565 | Depends on insurance |
| 🇺🇸 United States (Medicare) | $2,355 negotiated price per 30-day supply in 2026; $583.77 per SureClick pen (CMS price file); 2023 list price $7,106 per 30-day supply | $2,335 | Depends on the Part D plan |
| 🇺🇸 United States (pharmacy cost) | $2,083.62477 per mL = per 50 mg pen (CMS NADAC, Oct 28, 2026) | $8,334 | — |
| 🇬🇧 United Kingdom | £715.00 for 4 (NHS price, since 2006); biosimilars Erelzi £643.50, Benepali £656.00 for 4 (hospital-only packs) | $958 · biosimilar $862 | Usually supplied through the hospital |
| 🇫🇷 France | €472.63 for 4 pens (official price excluding dispensing fee); biosimilars Benepali, Erelzi and Nepexto at the same price | $528 | 35% of the price unless a complementary insurer covers it (65% reimbursed) |
| 🇩🇪 Germany | Statutory price ceiling (Festbetrag) €862.63 for 4 × 50 mg; Enbrel from €816.19, Erelzi €814.92, Benepali €818.67 (pharmacy prices, list of Nov 1, 2026) | $912 · biosimilar $910 | €10 co-payment per pack (10%, max. €10) |
| 🇨🇭 Switzerland | Enbrel CHF 455.15 for 2 pens; Benepali CHF 771.05 for 4; Nepexto CHF 685.45 for 4 (public prices) | $1,106 · biosimilar $833 | 10% share after the annual deductible |
| 🇦🇹 Austria | Enbrel €606.50 for 4 pens; biosimilars Erelzi €477.35, Benepali €611.70 (social-insurance prices excl. VAT; effective price may be lower under a price model) | $678 · biosimilar $533 | €7.55 prescription fee per pack; only for the listed indications |
| 🇳🇱 Netherlands | €550.35 for 4 pens (average pharmacy price) | $615 | Reimbursed under conditions; counts toward the annual deductible |
We compare prices; we do not recommend where to buy medicine. Whether to start, stop or switch a biologic — including to a biosimilar — is a decision for your rheumatologist or dermatologist.
Amgen's list price is $2,141.37 per pen (as of September 8, 2026). Pharmacies paid on average $2,083.62 per pen in late October 2026 (NADAC). Medicare's negotiated price, in force since January 1, 2026, is $2,355 for a 30-day supply — 67% below the 2023 list price of $7,106 — and $583.77 per SureClick pen in CMS's price file. For Medicare patients the drug maker refunds pharmacies the difference afterward (CMS).
Germany sets one statutory price ceiling (Festbetrag) for etanercept: €862.63 for four 50 mg doses in the list of November 1, 2026. Enbrel and the biosimilars Benepali, Erelzi and Nepexto are listed at or below it, from €814.92. Statutory insurance pays up to the ceiling (§ 31(2) SGB V); the co-payment is 10%, capped at €10 per pack (€15 from 2027). France lists Enbrel at €472.63 for four pens, the Netherlands at €550.35.
CMS's price file of November 2, 2026 adjusts Enbrel's negotiated price for inflation from January 1, 2027: $2,418.70 for a 30-day supply, $599.56 per SureClick pen.
Amgen lists Enbrel at $2,141.37 per 50 mg pen (September 8, 2026) — about $8,565 for four weekly doses. Medicare pays a negotiated $583.77 per pen in 2026, about $2,335 for four (CMS). Official prices for four pens elsewhere: €472.63 in France, €550.35 in the Netherlands, £715.00 in the UK and from €816.19 in Germany — roughly $528 to $958 at ECB rates.
Yes, in Europe. Germany's statutory price list includes the biosimilars Benepali, Erelzi and Nepexto at or below the ceiling of €862.63 for four doses; Switzerland lists Benepali at CHF 771.05 and Nepexto at CHF 685.45 for four pens. The US national pharmacy-price survey (NADAC, October 28, 2026) lists only Enbrel.
$2,355 for a 30-day supply in 2026, 67% below the 2023 list price of $7,106 (CMS). CMS's price file sets $583.77 per SureClick pen, rising to $599.56 on January 1, 2027 with an inflation adjustment.
Etanercept has a statutory price ceiling (Festbetrag) of €862.63 for four 50 mg doses (list of November 1, 2026). Enbrel is listed from €816.19, the biosimilar Erelzi from €814.92. Statutory insurance pays up to the ceiling; insured patients pay a 10% co-payment, capped at €10 per pack (€15 from 2027).
France reimburses 65% of the official price. In Switzerland insured patients pay a 10% share after their deductible, and in the Netherlands it is reimbursed under conditions and counts toward the annual deductible. In the UK the NHS pack is hospital-only, so it is usually supplied through the hospital. In the US it depends on the insurance plan.
Wellness Vision does not sell medicine, recommend pharmacies or suppliers, or take payments from drug makers. Every price above comes from the official source cited; conversions and per-30-tablet figures are our own calculations, shown with their formula. This is a cost comparison, not medical advice.
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