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No sponsorships, referrals or clinic partnerships
EpiPen, insulin & Ozempic prices refreshed October 2026
Cost comparison only — not medical advice
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Drug Prices

Entresto Price by Country: $295 for Medicare, €110 in France

The same heart-failure tablet, sacubitril/valsartan 97/103 mg twice a day — priced from official databases in six places, with the new US generic.

November 2026 · Updated November 3, 2026 · By Wellness Vision 5 min read 12 sources

Researched with AI assistance; every figure is checked against the primary source cited on this page before publishing. How we work →

Key Takeaways

  • $295 for Medicare, $628 list in 2023 — for 2026 only. Medicare's negotiated price for a 30-day supply applies from January 1, 2026, 53% below the 2023 list price. CMS's price file ends it on December 31, 2026 and marks Entresto as deselected.
  • A US generic costs pharmacies about $35 a month. US pharmacies paid $0.58038 per generic sacubitril/valsartan 97/103 mg tablet in late October 2026 — about $35 for 60 — against $11.59281 per brand Entresto tablet, about $696 (CMS NADAC; our calculation).
  • Europe: about $131 to $170 for the same month of brand Entresto. Official prices converted to 60 tablets at ECB rates: UK $131, France $132, the Netherlands $139, Switzerland $170 (our calculation for packs of 56).
  • Germany has no price ceiling for it; insured patients pay the usual €5–€10 co-payment per pack.

Entresto Price by Country (November 2026)

Entresto 97/103 mg, the target dose taken twice a day, so 30 days = 60 tablets. Each country's own official price; where the official pack has 56 tablets or the source gives a price per tablet, we convert to 60 tablets (our calculation: pack price ÷ tablets × 60). US dollars at European Central Bank reference rates of October 30, 2026. We could not verify a current US list price from the maker, so we show the 2023 list price reported by CMS.

30 days = 60 tablets of 97/103 mg. US: CMS negotiated price and 2023 list price (2026 fact sheet), CMS NADAC (October 28, 2026). UK: NHS dm+d. France: BDPM official price excluding dispensing fee (September 29, 2026). Switzerland: BAG public price. Netherlands: Zorginstituut average price per pack of 56 (to November 1, 2026). Converted at ECB rates of October 30, 2026; packs of 56 and per-tablet costs scaled to 60 tablets (our calculation).
CountryOfficial price30 days in US dollarsWhat a patient typically pays
🇺🇸 United States (Medicare)$295 negotiated price per 30-day supply, Jan 1 – Dec 31, 2026; 2023 list price $628 (CMS)$295Depends on the Part D plan
🇺🇸 United States (pharmacy cost)Entresto $11.59281 per tablet; generic sacubitril/valsartan $0.58038 per tablet (CMS NADAC, Oct 28, 2026)$696 · generic $35Depends on insurance
🇬🇧 United Kingdom£91.56 for 56 tablets (NHS price, since Dec 16, 2015)$131£9.90 per item in England; free in Scotland, Wales and Northern Ireland
🇫🇷 France€110.03 for 56 tablets (official price excluding dispensing fee)$13235% of the price unless a complementary insurer covers it (65% reimbursed)
🇨🇭 SwitzerlandCHF 130.25 for 56 tablets (public price; also 168 for CHF 358.00)$17010% share after the annual deductible
🇦🇹 Austria€140.85 for 56 tablets (social-insurance price excl. VAT; effective price may be lower under a price model)$169€7.55 prescription fee per pack; insurer approval needed first
🇳🇱 Netherlands€115.81 for 56 tablets (average pharmacy price)$139Reimbursed under conditions; counts toward the annual deductible
🇩🇪 GermanyNo statutory price ceiling (Festbetrag) for sacubitril/valsartan—€5–€10 co-payment per pack (10%, min. €5, max. €10)

We compare prices; we do not recommend where to buy medicine. Whether to take or switch a heart-failure medicine is a decision for your cardiologist.

What the Numbers Mean

A negotiated price that lasts one year

Entresto was among the first ten drugs whose price Medicare negotiated under the Inflation Reduction Act: $295 for a 30-day supply from January 1, 2026, 53% below the 2023 list price of $628 (CMS). CMS's maximum-fair-price file of November 2, 2026 ends that price on December 31, 2026 and marks Entresto as deselected. Pharmacies still buy brand Entresto for about $696 per 60 tablets (NADAC); for Medicare patients the drug maker refunds the difference afterward (CMS).

The generic is already in US pharmacies

The national pharmacy-price survey of October 28, 2026 lists generic sacubitril/valsartan 97/103 mg at $0.58038 per tablet — about $35 for 60 tablets, roughly a twentieth of the brand. In the UK, France, Switzerland and the Netherlands the official lists we checked show only the brand.

Europe: one official price per pack

The NHS price of £91.56 for 56 tablets has not changed since December 2015. France lists €110.03, the Netherlands €115.81 and Switzerland CHF 130.25 for the same pack. Germany has no statutory price ceiling (Festbetrag) for the combination; insured patients pay 10% of the price, at least €5 and at most €10 per pack, rising to €7.50 and €15 in 2027.

Frequently Asked Questions

How much does Entresto cost in the US compared with other countries?

Medicare pays a negotiated $295 for a 30-day supply of Entresto in 2026; the 2023 list price was $628 (CMS). US pharmacies pay about $696 for 60 brand tablets and about $35 for 60 generic tablets (CMS NADAC, October 28, 2026). Official prices for brand Entresto elsewhere: £91.56 for 56 tablets in the UK, €110.03 in France, €115.81 in the Netherlands and CHF 130.25 in Switzerland — roughly $131 to $170 for 60 tablets at ECB rates.

Is there a generic Entresto (sacubitril/valsartan)?

In the US, yes: the national pharmacy-price survey lists generic sacubitril/valsartan 97/103 mg at $0.58038 per tablet (NADAC, October 28, 2026). The official lists we checked in the UK, France, Switzerland and the Netherlands show only the brand.

Does Medicare's negotiated price continue in 2027?

No, according to CMS's maximum-fair-price file of November 2, 2026: the $295 price for Entresto runs from January 1 to December 31, 2026 and the drug is marked as deselected. What Medicare patients pay in 2027 will depend on their Part D plan.

Why is Medicare's price lower than what pharmacies pay?

The $295 is Medicare's negotiated price for a 30-day supply. NADAC (about $696 for 60 brand tablets) measures what pharmacies pay to acquire the drug; under the negotiation program the drug maker refunds pharmacies the difference afterwards (CMS), so the two numbers measure different things.

What do patients pay elsewhere?

In England each prescription item costs £9.90. France reimburses 65% of the official price. In Germany statutory insurance covers it with a co-payment of 10% of the price, at least €5 and at most €10 per pack. In Switzerland insured patients pay a 10% share after their deductible, and in the Netherlands it is reimbursed under conditions and counts toward the annual deductible.

Sources

  1. CMS — Negotiated prices for initial price applicability year 2026 (fact sheet): Entresto $295 negotiated price, $628 list price (2023), 30-day supply, 53% lower
  2. CMS — Selected drug list and maximum fair price data file (November 2, 2026): Entresto price effective January 1 to December 31, 2026, update type “Deselect”
  3. CMS — Medicare Drug Price Negotiation Program: final guidance and effectuation of the negotiated price (refunds from drug makers to pharmacies)
  4. CMS — NADAC (National Average Drug Acquisition Cost), as of October 28, 2026: Entresto 97/103 mg $11.59281 per tablet; sacubitril-valsartan 97-103 mg (generic) $0.58038
  5. NHS dm+d — Entresto 97 mg/103 mg tablets, 56: NHS indicative price £91.56 (since December 16, 2015)
  6. NHS Business Services Authority — prescription charge £9.90 per item (England)
  7. Base de données publique des médicaments — Entresto 97 mg/103 mg, 4 × 14 tablets: €110.03 excluding dispensing fee, 65% reimbursed (updated September 29, 2026)
  8. Federal Office of Public Health (BAG) — Spezialitätenliste: Entresto 200 mg (97/103 mg), 56 tablets, public price CHF 130.25; 168 tablets CHF 358.00; cost share 10%
  9. Austrian social insurance (Dachverband) — Erstattungskodex monthly data, Nov 2026: Entresto 97 mg/103 mg Filmtabl. €140.85 (price model) (social-insurance price excl. VAT; chief-physician approval (RE1))
  10. oesterreich.gv.at — prescription fee (Rezeptgebühr) €7.55 per pack since January 1, 2026
  11. Zorginstituut Nederland — Medicijnkosten.nl: Entresto 97/103 mg (EU/1/15/1058/006), average price €115.81 per pack, reimbursed under conditions (updated to November 1, 2026)
  12. European Medicines Agency — Entresto product information: EU/1/15/1058/006 = 56 film-coated tablets
  13. BfArM / GKV-Spitzenverband — Festbetrag list as of October 15, 2026 (no entry for sacubitril/valsartan)
  14. European Central Bank — reference rates, October 30, 2026 (1 US dollar = €0.89509 = £0.74633 = CHF 0.82295)

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Wellness Vision Editorial Policy

Wellness Vision does not sell medicine, recommend pharmacies or suppliers, or take payments from drug makers. Every price above comes from the official source cited; conversions and per-30-tablet figures are our own calculations, shown with their formula. This is a cost comparison, not medical advice.

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